Phellinus rimosus. Protects Carbon Tetrachloride-Induced Chronic Hepatotoxicity In Rats: Antioxidant Defense Mechanism
نویسندگان
چکیده
منابع مشابه
Hepatoprotective and Antioxidant Effects of Eupatorium ayapana against Carbon Tetrachloride Induced Hepatotoxicity in Rats
The present study was carried out to evaluate the hepatoprotective and antioxidant effect of the methanol extract of Eupatorium ayapana (MEEA) (Family- Asteraceae) leaves in Wistar albino rats. The different groups of animals were administered with carbon tetrachloride (CCl4) at 72 h interval. The MEEA at 100, 200 and 300 mg/kg and silymarin 25 mg/kg were administered to the CCl4 treated ...
متن کاملPotential Hepatoprotective Effect and Antioxidant Role of Methanol Extract of Oldenlandia Umbellata in Carbon Tetrachloride Induced Hepatotoxicity in Wistar Rats
The present work examines the protective mechanisms of methanol extract of Oldenlandia umbellata (MEOU) in carbon tetrachloride intoxicated rats. Rats were treated with carbon tetrachloride at the dose of 1 ml/kg body weight intraperitonially once in every 72 hrs for 16 days. The hepatoprotective activity of methanol extract of Oldenlandia umbellata was evaluated by measuring levels of serum ma...
متن کاملAntioxidant and antiapoptotic effects of capsaicin against carbon tetrachloride-induced hepatotoxicity in rats.
The aim of the study was to evaluate the potential hepatoprotective utility of capsaicin against carbon tetrachloride (CCl₄)-induced liver injury and to explore the possible mechanisms whereby this agent mediated its beneficial effects. We randomized 40 rats into four groups for treatment with corn oil, CCl₄, capsaicin and both CCl₄ and capsaicin, respectively, for 8 weeks. At the end of the ex...
متن کاملMechanism of carbon tetrachloride-induced hepatotoxicity. Hepatocellular damage by reactive carbon tetrachloride metabolites.
CCl4-induced liver damage was modeled in monolayer cultures of rat primary hepatocytes with a focus on involvement of covalent binding of CCl4 metabolites to cell components and/or peroxidative damage as the cause of injury. (1) Covalent binding of 14C-labeled metabolites was detected in hepatocytes immediately after exposure to CCl4. (2) Low oxygen partial pressure increased the reductive meta...
متن کاملhepatoprotective and antioxidant effects of eupatorium ayapana against carbon tetrachloride induced hepatotoxicity in rats
the present study was carried out to evaluate the hepatoprotective and antioxidant effect of the methanol extract of eupatorium ayapana (meea) (family- asteraceae) leaves in wistar albino rats. the different groups of animals were administered with carbon tetrachloride (ccl4) at 72 h interval. the meea at 100, 200 and 300 mg/kg and silymarin 25 mg/kg were administered to the ccl4 treated rats....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pharmaceutical Biology
سال: 2006
ISSN: 1388-0209,1744-5116
DOI: 10.1080/13880200600798569